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1

Expression inE. coliand tissue distribution of the human homologue of the mouse Ke 6 gene, 17β-hydroxysteroid dehydrogenase type 8

Shuji Ohno, Kouki Nishikawa, Yoko Honda, Shizuo Nakajin

Journal:

Molecular and Cellular Biochemistry

Année:

2008

Langue:

english

Fichier:

PDF, 328 KB

english, 2008

2

Sequence and expression of 11β-hydroxysteroid dehydrogenase type 1 cDNA cloned from pig testis

Shuji Ohno, Masanori Ohta, Yoko Honda, Shizuo Nakajin

Journal:

Molecular and Cellular Biochemistry

Année:

2010

Langue:

english

Fichier:

PDF, 1.64 MB

english, 2010

3

Deletion of 12 carboxyl-terminal residues from pig 3α/β,20β-hydroxysteroid dehydrogenase affects steroid metabolism

Shizuo Nakajin, Masaya Itoda, Shuji Ohno, Noriko Takase, Satoshi Toyoshima, Michael E Baker

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Année:

2001

Langue:

english

Fichier:

PDF, 253 KB

english, 2001

4

Purification and properties of 17α-hydroxylase from microsomes of pig adrenal: A scond C21side-chain cleavage system

Shizuo Nakajin, Masato Shinoda, Peter F. Hall

Journal:

Biochemical and Biophysical Research Communications

Année:

1983

Langue:

english

Fichier:

PDF, 886 KB

english, 1983

5

Peptide alignment of the porcine 21-hydroxylase cytochrome P-450 using a cDNA sequence of the corresponding bovine enzyme

Michael J. Bienkowski, Mitsuru Haniu, Shizuo Nakajin, Masato Shinoda, Kazutoshi Yanagibashi, Peter F. Hall, John E. Shively

Journal:

Biochemical and Biophysical Research Communications

Année:

1984

Langue:

english

Fichier:

PDF, 408 KB

english, 1984

6

Cytochrome b5 promotes the synthesis of Δ16-C19 steroids by homogeneous cytochrome P-450 C21 side-chain cleavage from pig testis

Shizuo Nakajin, Masayuki Takahashi, Masato Shinoda, Peter F. Hall

Journal:

Biochemical and Biophysical Research Communications

Année:

1985

Langue:

english

Fichier:

PDF, 311 KB

english, 1985

7

Amino terminal sequence analysis of human placenta aromatase

Shiuan Chen, John E. Shively, Shizuo Nakajin, Masato Shinoda, Peter F. Hall

Journal:

Biochemical and Biophysical Research Communications

Année:

1986

Langue:

english

Fichier:

PDF, 368 KB

english, 1986

8

Side-chain cleavage of C21 steroids to C19 steroids by testicular microsomal cytochrome P-450: 17α-Hydroxy C21 steroids as obligatory intermediates

Shizuo Nakajin, Peter F. Hall

Journal:

Journal of Steroid Biochemistry

Année:

1981

Langue:

english

Fichier:

PDF, 535 KB

english, 1981

9

Side-chain cleavage of C21 steroids by testicular microsomal cytochrome P-450 (17α-hydroxylase/lyase): Involvement of heme

Nakajin Shizuo, Peter F. Hall

Journal:

Journal of Steroid Biochemistry

Année:

1983

Langue:

english

Fichier:

PDF, 362 KB

english, 1983

10

Purification and characterization of pig adrenal 20α-hydroxysteroid dehydrogenase

Nakajin Shizuo, Kawai Yasuko, Ohno Shuji, Shinoda Masato

Journal:

Journal of Steroid Biochemistry

Année:

1989

Langue:

english

Fichier:

PDF, 926 KB

english, 1989

11

Purification and characterization of aromatase from human placenta

Peter F. Hall, Shiuan Chen, Shizuo Nakajin, Masato Shinoda, John E. Shively

Journal:

Année:

1987

Langue:

english

Fichier:

PDF, 604 KB

english, 1987

12

Tributyltin chloride suppresses the P450cl7 transcription involved in testosterone production induced by gonadotropin stimulation in cultured pig Leydig cells

Yonako Nakajima, Go Sato, Shuji Ohno, Shizuo Nakajin

Journal:

Environmental Toxicology and Pharmacology

Année:

2005

Langue:

english

Fichier:

PDF, 234 KB

english, 2005

13

3α/β,20β-Hydroxysteroid dehydrogenase (porcine testicular carbonyl reductase) also has a cysteine residue that is involved in binding of cofactor NADPH

Takuya Sugiyama, Shuji Ohno, Debashis Ghosh, Shizuo Nakajin

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Année:

2004

Langue:

english

Fichier:

PDF, 246 KB

english, 2004

14

Flavonoid inhibition of overexpressed human 3β-hydroxysteroid dehydrogenase type II

Shuji Ohno, Noriko Matsumoto, Masatada Watanabe, Shizuo Nakajin

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Année:

2004

Langue:

english

Fichier:

PDF, 157 KB

english, 2004

15

Sequence of pig 17β-hydroxysteroid dehydrogenase Type3 cDNA and its expression in mammalian cells

Shuji Ohno, Yoko Honda, Yonako Nakajima, Shizuo Nakajin

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Année:

2006

Langue:

english

Fichier:

PDF, 243 KB

english, 2006

16

Genistein administration decreases serum corticosterone and testosterone levels in rats

Shuji Ohno, Yonako Nakajima, Koichi Inoue, Hiroyuki Nakazawa, Shizuo Nakajin

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 239 KB

english, 2003

17

Mono-(2-ethylhexyl) phthalate (MEHP) induces nuclear receptor 4A subfamily in NCI-H295R cells: A possible mechanism of aromatase suppression by MEHP

Mariko Noda, Shuji Ohno, Shizuo Nakajin

Journal:

Molecular and Cellular Endocrinology

Année:

2007

Langue:

english

Fichier:

PDF, 719 KB

english, 2007

18

Triphenyltin and Tributyltin inhibit pig testicular 17β-hydroxysteroid dehydrogenase activity and suppress testicular testosterone biosynthesis

Shuji Ohno, Yonako Nakajima, Shizuo Nakajin

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 181 KB

english, 2005

19

Effects of bisphenol A on the expression of cytochrome P450 aromatase (CYP19) in human fetal osteoblastic and granulosa cell-like cell lines

Masatada Watanabe, Shuji Ohno, Shizuo Nakajin

Journal:

Toxicology Letters

Année:

2012

Langue:

english

Fichier:

PDF, 342 KB

english, 2012

20

Purification to homogeneity of aromatase from human placenta

Shizuo Nakajin, Masato Shinoda, Peter F. Hall

Journal:

Biochemical and Biophysical Research Communications

Année:

1986

Langue:

english

Fichier:

PDF, 976 KB

english, 1986

21

Effects of flavonoid phytochemicals on cortisol production and on activities of steroidogenic enzymes in human adrenocortical H295R cells

Shuji Ohno, Satoshi Shinoda, Satoshi Toyoshima, Hiroyuki Nakazawa, Tsunehisa Makino, Shizuo Nakajin

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Année:

2002

Langue:

english

Fichier:

PDF, 150 KB

english, 2002

22

Effect of phthalate esters and alkylphenols on steroidogenesis in human adrenocortical H295R cells

Shizuo Nakajin, Satoshi Shinoda, Shuji Ohno, Hiroyuki Nakazawa, Tsunehisa Makino

Journal:

Environmental Toxicology and Pharmacology

Année:

2001

Langue:

english

Fichier:

PDF, 200 KB

english, 2001

23

Binding of Triton X-100 to purified cytochrome P-450scc and enhancement of the cholesterol side chain cleavage activity

Shizuo Nakajin, Yoshiyuki Ishii, Masato Shinoda, Mikio Shikita

Journal:

Biochemical and Biophysical Research Communications

Année:

1979

Langue:

english

Fichier:

PDF, 426 KB

english, 1979

24

Mono-(2-ethylhexyl) phthalate induces NR4A subfamily and GIOT-1 gene expression, and suppresses CYP19 expression in human granulosa-like tumor cell line KGN

Shuji Ohno, Fumihiko Yukinawa, Mariko Noda, Shizuo Nakajin

Journal:

Toxicology Letters

Année:

2009

Langue:

english

Fichier:

PDF, 321 KB

english, 2009

25

Direct expression of pig testicular (20β)-hydroxysteroid dehydrogenase in Escherichia coli

Nakajin, Shizuo, Nakajima, Takashi, Uchida, Mihoko, Ohno, Shuji, Shinoda, Masato

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Année:

1995

Langue:

english

Fichier:

PDF, 2.26 MB

english, 1995

26

Purification and characterization of 3α/β-hydroxysteroid dehydrogenase from mature porcine testicular cytosol

Nakajin, Shizuo, Fujita, Yoshiko, Ohno, Shuji, Uchida, Mihoko, Aoki, Masatada, Shinoda, Masato

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Année:

1994

Langue:

english

Fichier:

PDF, 817 KB

english, 1994

27

20β-hydroxysteroid dehydrogenase of neonatal pig testis: 3α/β-hydroxysteroid dehydrogenase activities catalyzed by highly purified enzyme

Ohno, Shuji, Nakajin, Shizuo, Shinoda, Masato

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Année:

1991

Langue:

english

Fichier:

PDF, 678 KB

english, 1991

28

Crystallization and preliminary x-ray diffraction studies of a mammalian steroid dehydrogenase

Ghosh, Debashis, Erman, Mary, Pangborn, Walter, Duax, William L., Nakajin, Shizuo, Ohno, Shuji, Shinoda, Masato

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Année:

1993

Langue:

english

Fichier:

PDF, 198 KB

english, 1993

29

Inhibitory effect of some imidazole antifungal compounds on the synthesis of 16-ene-C19-steroid catalyzed by pig testicular microsomes

Nakajin, Shizuo, Takahashi, Kazuaki, Shinoda, Masato

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Année:

1991

Langue:

english

Fichier:

PDF, 374 KB

english, 1991

30

Purification of leukocytosis-promoting substance from bovine parotid gland extract

Shinoda, Masato, Nakajin, Shizuo, Oikawa, Takayuki, Shimizu, Motoyuki, Kamogawa, Asahi

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Année:

1979

Langue:

english

Fichier:

PDF, 231 KB

english, 1979

31

Immunochemical distribution and immunohistochemical localization of 20β-hydroxysteroid dehydrogenase in neonatal pig tissues

Kobayashi, Keiko, Ohno, Shuji, Shinoda, Masato, Toyoshima, Satoshi, Nakajin, Shizuo

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Année:

1996

Langue:

english

Fichier:

PDF, 612 KB

english, 1996

32

Ontogeny of testicular steroid dehydrogenase enzymes in pig (3α/β-, 20α- and 20β-): Evidence for two forms of 3α/β-hydroxysteroid dehydrogenase

Ohno, Shuji, Nakajin, Shizuo, Shinoda, Masato

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Année:

1992

Langue:

english

Fichier:

PDF, 741 KB

english, 1992

33

3α-Hydroxysteroid dehydrogenase activity catalyzed by purified pig adrenal 20α-hydroxysteroid dehydrogenase

Nakajin, Shizuo, Fujii, Shigeo, Ohno, Shuji, Shinoda, Masato

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Année:

1992

Langue:

english

Fichier:

PDF, 517 KB

english, 1992

34

Steroid 21-hydroxylase (cytochrome P-450) from porcine adrenocortical microsomes: microsequence analysis of cysteine-containing peptides

Yuan, Pau Miau, Nakajin, Shizuo, Haniu, Mitsuru, Hall, Peter F., Shively, John E.

Journal:

Année:

1983

Langue:

english

Fichier:

PDF, 1.16 MB

english, 1983

35

Microsomal cytochrome P-450 from neonatal pig testis: two enzymic activities (17.alpha.-hydroxalase and C17,20 associated with one protein

Nakajin, Shizuo, Shively, John, Yuan, Pau-Miau, Hall, Peter F.

Journal:

Année:

1981

Langue:

english

Fichier:

PDF, 1.74 MB

english, 1981

36

Quantitative determination and tissue distribution of human 11β-hydroxysteroid dehydrogenase, hexose-6-phosphate dehydrogenase, glucose-6-phosphate transporter, glucocorticoid receptor and mineralocorticoid receptor mRNAs

Ohno, Shuji, Ohta, Masanori, Nakajin, Shizuo

Journal:

Hormone Molecular Biology and Clinical Investigation

Année:

2010

Langue:

english

Fichier:

PDF, 152 KB

english, 2010

37

Quantitative Analysis of UGT2B28 mRNA Expression by Real-Time RT-PCR and Application to Human Tissue Distribution Study

Ohno, Shuji, Nakajin, Shizuo

Journal:

Drug Metabolism Letters

Année:

2011

Langue:

english

Fichier:

PDF, 534 KB

english, 2011

38

Mutation of threonine-241 to proline eliminates autocatalytic modification of human carbonyl reductase

SCIOTTI, Michel A., NAKAJIN, Shizuo, WERMUTH, Bendicht, BAKER, Michael E.

Journal:

Biochemical Journal

Année:

2000

Langue:

english

Fichier:

PDF, 114 KB

english, 2000

39

Mutation of tyrosine-194 and lysine-198 in the catalytic site of pig 3α/β,20β-hydroxysteroid dehydrogenase

NAKAJIN, Shizuo, TAKASE, Noriko, OHNO, Shuji, TOYOSHIMA, Satoshi, BAKER, Michael E.

Journal:

Biochemical Journal

Année:

1998

Langue:

english

Fichier:

PDF, 348 KB

english, 1998

40

Mutation of threonine-241 to proline eliminates autocatalytic modification of human carbonyl reductase

SCIOTTI, Michel A., NAKAJIN, Shizuo, WERMUTH, Bendicht, BAKER, Michael E.

Journal:

Biochemical Journal

Année:

2000

Langue:

english

Fichier:

PDF, 114 KB

english, 2000

41

Purification and Characterization of 5.ALPHA.-Dihydrotestosterone 3.BETA.-Hydroxysteroid Dehydrogenase from Mature Pig Testicular Cytosol.

NAKAJIN, Shizuo, ISHII, Akihiro, SHINODA, Masato

Journal:

Biological & Pharmaceutical Bulletin

Année:

1994

Fichier:

PDF, 1.15 MB

1994

42

Antioxidative Effect of Sesamol and Related Compounds on Lipid Peroxidation.

UCHIDA, Mihoko, NAKAJIN, Shizuo, TOYOSHIMA, Satoshi, SHINODA, Masato

Journal:

Biological & Pharmaceutical Bulletin

Année:

1996

Fichier:

PDF, 585 KB

1996

43

Carbonyl Reductase Activity Exhibited by Pig Testicular 20.BETA.-Hydroxysteroid Dehydrogenase.

NAKAJIN, Shizuo, TAMURA, Fumihiro, TAKASE, Noriko, TOYOSHIMA, Satoshi

Journal:

Biological & Pharmaceutical Bulletin

Année:

1997

Fichier:

PDF, 622 KB

1997

44

An NADPH-Dependent Reductase in Neonatal Pig Testes That Metabolizes Androgens and Xenobiotics.

NAKAJIN, Shizuo, MINAMIKAWA, Noriko, BAKER, Michael E., TOYOSHIMA, Satoshi

Journal:

Biological & Pharmaceutical Bulletin

Année:

1998

Fichier:

PDF, 890 KB

1998

45

Evidence of Autophosphorylation in Txk: Y91 Is an Autophosphorylation Site

Kashiwakura, Jun-ichi, Suzuki, Noboru, Takeno, Mitsuhiro, Itoh, Saotomo, Oku, Teruaki, Sakane, Tsuyoshi, Nakajin, Shizuo, Toyoshima, Satoshi

Journal:

Biological & Pharmaceutical Bulletin

Année:

2002

Langue:

english

Fichier:

PDF, 66 KB

english, 2002

46

The Role of Protein Kinase C in the Transient Association of p57, a Coronin Family Actin-Binding Protein, with Phagosomes

Itoh, Saotomo, Suzuki, Kensuke, Nishihata, Jun, Iwasa, Mitsusada, Oku, Teruaki, Nakajin, Shizuo, Nauseef, William Michael, Toyoshima, Satoshi

Journal:

Biological & Pharmaceutical Bulletin

Année:

2002

Langue:

english

Fichier:

PDF, 457 KB

english, 2002

47

Participation of cytochrome b5 electron transport system coupled with .DELTA.5-3 .BETA.-hydroxysteroid dehydrogenase on cytochrome P-450 monooxygenase reactions of guinea pig adrenal microsomes.

NAKAJIN, SHIZUO, SHINODA, MASATO

Journal:

Journal of Pharmacobio-Dynamics

Année:

1983

Fichier:

PDF, 642 KB

1983

48

Purification of a leukocytosis promotion-inhibiting factor from bovine bile.

SHINODA, MASATO, KUSHI, YASUNORI, SHIMIZU, MOTOYUKI, NAKAJIN, SHIZUO, YAMASHITA, SABURO

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

1982

Fichier:

PDF, 581 KB

1982

49

20.BETA.-Hydroxysteroid dehydrogenase of neonatal pig testis: Cofactor requirement and stereospecificity of hydrogen transfer from nicotinamide adenine dinucleotide phosphate, reduced form.

NAKAJIN, Shizuo, OHNO, Shuji, AOKI, Masatada, SHINODA, Masato

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

1989

Fichier:

PDF, 547 KB

1989

50

Effects of Various Chemicals Including Endocrine Disruptors and Analogs on the Secretion of Th1 and Th2 Cytokines from Anti CD3-Stimulated Mouse Spleen Cells

Yano, Kazuma, Ohno, Shuji, Nakajima, Yonako, Toyoshima, Satoshi, Nakajin, Shizuo

Journal:

JOURNAL OF HEALTH SCIENCE

Année:

2003

Langue:

english

Fichier:

PDF, 198 KB

english, 2003